Therapeutic Window:
The therapeutic window refers to the range of drug concentrations in the body that provide the desired therapeutic effect without reaching toxic levels. It is the range between the minimum effective concentration (MEC) and the minimum toxic concentration (MTC) of a drug.
Therapeutic Index:
The therapeutic index, also known as the therapeutic ratio, is a quantitative measure of the relative safety of a drug. It is calculated by dividing the median lethal dose (LD50) by the median effective dose (ED50) of a drug. A higher therapeutic index indicates a wider margin of safety, as it signifies a greater difference between the doses required for therapeutic effects and those that cause toxicity.