Definition: Sepsis is a potentially life-threatening condition that occurs when the body’s response to an infection damages its own tissues and organs.


Sepsis is a severe inflammatory response that can develop when an infection, which can originate from various sources such as bacteria, viruses, or fungi, enters the bloodstream and spreads throughout the body. It is characterized by a dysregulated immune response that can lead to organ dysfunction, tissue damage, and, in severe cases, septic shock.


The signs and symptoms of sepsis can vary from mild to severe and can develop rapidly. Some common symptoms include:

  • Fever or low body temperature
  • Rapid heart rate
  • Difficulty breathing
  • Confusion or disorientation
  • Extreme pain or discomfort
  • Clammy or sweaty skin


Sepsis is usually triggered by an infection, which can occur in different parts of the body, such as the lungs, urinary tract, skin, or abdominal organs. Common sources of infection leading to sepsis include pneumonia, urinary tract infections, abdominal infections (e.g., appendicitis, peritonitis), and bloodstream infections (e.g., through intravenous lines or catheters).


Early detection and prompt treatment are crucial in sepsis management. Treatment may include:

  • Administration of antibiotics to target the underlying infection
  • Intravenous fluids to maintain blood pressure
  • Supplemental oxygen therapy
  • Organ support, such as mechanical ventilation or dialysis
  • Surgical intervention to remove the source of infection, if necessary

Severe cases of sepsis may require admission to an intensive care unit (ICU) for close monitoring and advanced care. In some instances, supportive care techniques like fluid therapy and vasopressor medications may be employed to stabilize the patient’s condition.

It is important to note that sepsis can be a life-threatening condition, and immediate medical attention should be sought if sepsis is suspected.