Narcan

Narcan is a medication used to rapidly reverse the effects of opioid overdose.

Uses

Narcan is primarily used for:

  • Reversing respiratory depression caused by opioids
  • Countering the sedative effects of opioids
Mechanism of Action

Narcan works by:

  • Competitively binding to opioid receptors in the brain
  • Blocking the effects of opioids
  • Increasing respiration and waking the individual from opioid-induced sedation
Administration

Narcan can be administered through:

  • Injection (intramuscular or intravenous)
  • Nasal spray
Side Effects

Common side effects of Narcan include:

  • Nausea or vomiting
  • Increase in blood pressure
  • Increased heart rate
Contraindications

Narcan may not be suitable for individuals who:

  • Are allergic to naloxone (the active ingredient)
  • Have a known sensitivity to N-acetyltryptamine, an ingredient in the nasal spray
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