Definition:

Lethal Catatonia is a rare and severe neuropsychiatric disorder characterized by a combination of catatonic symptoms and extreme hyperthermia. It is a life-threatening emergency condition that requires immediate medical intervention.

Subtypes:

  • Classic Lethal Catatonia: This subtype involves the presence of catatonic symptoms along with hyperthermia and autonomic instability.
  • Systemic Lethal Catatonia: In this subtype, catatonic symptoms are accompanied by autonomic dysfunction without significant hyperthermia.

Symptoms:

The symptoms of Lethal Catatonia may include:

  • Waxy flexibility (maintaining a position for an extended period)
  • Mutism (inability to speak)
  • Stupor (motionless and unresponsive)
  • Excitement (agitated behavior)
  • Posturing (assuming unusual or inappropriate body positions)
  • Hyperthermia (elevated body temperature)
  • Changes in blood pressure and heart rate
  • Sweating excessively

Causes:

The exact causes of Lethal Catatonia are not fully understood. However, there are several factors that may contribute to its development, including:

  • Underlying psychiatric disorders (such as schizophrenia or bipolar disorder)
  • Genetic predisposition
  • Neurological abnormalities
  • Prolonged immobility
  • Infection or other medical conditions
  • Medication changes or withdrawals

Treatment:

Lethal Catatonia is a medical emergency that requires immediate intervention. Treatment typically involves a multidisciplinary approach, including:

  • Hospitalization in an intensive care unit
  • Administration of intravenous fluids
  • Use of medications to control symptoms and reduce hyperthermia
  • Supportive care to ensure hydration and nutrition
  • Psychiatric evaluation and possible continuation of long-term treatment

Early recognition and prompt medical intervention are crucial to increase the chances of recovery and prevent life-threatening complications associated with Lethal Catatonia.