Definition of Human Chorionic Gonadotropin (hCG)

Human chorionic gonadotropin (hCG) is a hormone that is primarily produced by the placenta in pregnant women. It is a glycoprotein composed of an alpha and a beta subunit. The alpha subunit is similar to other hormones, while the beta subunit is specific to hCG.

Functions of hCG

hCG plays a crucial role in the early stages of pregnancy and has several important functions:

  1. Implantation and Maintenance of Pregnancy: hCG helps in the implantation of the fertilized egg into the uterine lining and supports the maintenance of the pregnancy.
  2. Stimulation of Progesterone: It stimulates the production of progesterone by the corpus luteum, which is essential for the development of the uterine lining and the prevention of menstruation during pregnancy.
  3. Promotion of Fetal Development: hCG promotes the development of the fetus by facilitating the production of other hormones, such as estrogen and testosterone.
  4. Diagnostic Marker for Pregnancy: The presence of hCG in the blood or urine is commonly used as a diagnostic marker for pregnancy testing.

Medical Uses of hCG

Aside from its natural functions during pregnancy, hCG also has medical applications:

  1. Fertility Treatment: hCG injections can be used to trigger ovulation in women undergoing fertility treatments, such as in vitro fertilization (IVF).
  2. Hormone Replacement Therapy: In certain cases, hCG is used in hormone replacement therapy for men and women to stimulate testosterone or estrogen production.
  3. Weight Loss Programs: Some weight loss programs incorporate hCG injections or oral intake, although the effectiveness and safety of this approach are still debated.

Overall, human chorionic gonadotropin (hCG) plays a vital role in pregnancy and has medical uses beyond reproductive health. Its various functions and potential applications make it a significant hormone in the human body.