Definition of Epithelium:

Epithelium is a type of tissue that covers the surfaces of organs, lines body cavities, and forms barriers between different environments in the body.

Characteristics of Epithelium:

1. Cellularity: Epithelium is composed of closely-packed cells with minimal extracellular matrix.

2. Polarity: Epithelial cells have an apical surface facing the lumen or external environment and a basal surface facing the underlying connective tissue.

3. Attachment: Epithelial cells are attached to each other and to the basement membrane through specialized junctions.

4. Avascularity: Epithelium lacks blood vessels and receives nutrients through diffusion from underlying connective tissue.

5. Regeneration: Epithelial cells have a high regenerative capacity, allowing for repair and renewal of the tissue.

Classification of Epithelium:

Epithelium can be classified based on the shape of its cells and the number of cell layers present.

Shapes of Epithelial Cells:

1. Squamous: Flat and scale-like cells.

2. Cuboidal: Cube-shaped cells.

3. Columnar: Tall, rectangular cells.

Layers of Epithelium:

1. Simple: Consists of a single layer of cells.

2. Stratified: Composed of multiple layers of cells.

3. Pseudostratified: Appears stratified but actually consists of a single layer of cells of varying heights.

Functions of Epithelium:

1. Protection: Epithelial layers act as barriers to protect underlying tissues from mechanical and chemical damage.

2. Absorption: Certain epithelia have specialized cells for absorbing nutrients and ions from the external environment.

3. Secretion: Epithelial cells can produce and release substances such as hormones, enzymes, and mucus.

4. Sensation: Epithelium contains sensory receptors that allow for the detection of stimuli such as touch, temperature, and taste.

Examples of Epithelial Tissues:

Simple squamous epithelium: Found in lung alveoli, blood vessels, and serous membranes.

Stratified squamous epithelium: Forms the outer layer of the skin and lines the oral cavity, esophagus, and vagina.

Simple cuboidal epithelium: Found in kidney tubules, glands, and the thyroid follicles.

Simple columnar epithelium: Lines the digestive tract, gallbladder, and parts of the respiratory system.

Pseudostratified columnar epithelium: Lines the respiratory tract, including the nasal cavity and trachea.