Definition of Epithelium:
Epithelium is a type of tissue that covers the surfaces of organs, lines body cavities, and forms barriers between different environments in the body.
Characteristics of Epithelium:
1. Cellularity: Epithelium is composed of closely-packed cells with minimal extracellular matrix.
2. Polarity: Epithelial cells have an apical surface facing the lumen or external environment and a basal surface facing the underlying connective tissue.
3. Attachment: Epithelial cells are attached to each other and to the basement membrane through specialized junctions.
4. Avascularity: Epithelium lacks blood vessels and receives nutrients through diffusion from underlying connective tissue.
5. Regeneration: Epithelial cells have a high regenerative capacity, allowing for repair and renewal of the tissue.
Classification of Epithelium:
Epithelium can be classified based on the shape of its cells and the number of cell layers present.
Shapes of Epithelial Cells:
1. Squamous: Flat and scale-like cells.
2. Cuboidal: Cube-shaped cells.
3. Columnar: Tall, rectangular cells.
Layers of Epithelium:
1. Simple: Consists of a single layer of cells.
2. Stratified: Composed of multiple layers of cells.
3. Pseudostratified: Appears stratified but actually consists of a single layer of cells of varying heights.
Functions of Epithelium:
1. Protection: Epithelial layers act as barriers to protect underlying tissues from mechanical and chemical damage.
2. Absorption: Certain epithelia have specialized cells for absorbing nutrients and ions from the external environment.
3. Secretion: Epithelial cells can produce and release substances such as hormones, enzymes, and mucus.
4. Sensation: Epithelium contains sensory receptors that allow for the detection of stimuli such as touch, temperature, and taste.
Examples of Epithelial Tissues:
– Simple squamous epithelium: Found in lung alveoli, blood vessels, and serous membranes.
– Stratified squamous epithelium: Forms the outer layer of the skin and lines the oral cavity, esophagus, and vagina.
– Simple cuboidal epithelium: Found in kidney tubules, glands, and the thyroid follicles.
– Simple columnar epithelium: Lines the digestive tract, gallbladder, and parts of the respiratory system.
– Pseudostratified columnar epithelium: Lines the respiratory tract, including the nasal cavity and trachea.