Definition:

Bupropion is a medication commonly used as an antidepressant and a smoking cessation aid. It belongs to the class of drugs known as aminoketones and is primarily prescribed to treat major depressive disorder and seasonal affective disorder (SAD).

Antidepressant Properties:

Bupropion acts by inhibiting the reuptake of norepinephrine and dopamine in the brain, thereby increasing their availability. This mechanism of action is thought to help alleviate symptoms of depression, such as low mood, loss of interest, and feelings of guilt or worthlessness.

Smoking Cessation Aid:

In addition to its antidepressant effects, bupropion is also approved for use as a smoking cessation aid. It aids in quitting smoking by reducing nicotine cravings and withdrawal symptoms. The exact way bupropion helps with smoking cessation is not fully understood, but it is believed to interact with brain chemicals involved in addiction.

Other Uses:

Bupropion may also be prescribed off-label for management of attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder. It is sometimes used as an alternative medication when other antidepressants have been ineffective or not tolerated by the patient.

Side Effects:

Common side effects of bupropion include dry mouth, headache, nausea, insomnia, and sweating. In some cases, it may also cause agitation, anxiety, or an increase in suicidal thoughts, particularly in children, adolescents, and young adults. It is crucial to discuss any potential risks and benefits with a healthcare professional before starting bupropion therapy.