Definition:

Atypical depression is a subtype of depression characterized by distinct symptoms that differ from those commonly associated with depression.

Symptoms:

Atypical depression is characterized by the following symptoms:

  • Mood reactivity: People with atypical depression typically experience an improved mood in response to positive events or experiences.
  • Increased appetite or weight gain: Atypical depression often leads to overeating and weight gain.
  • Hypersomnia: Individuals may experience excessive daytime sleepiness and increased need for sleep, often sleeping for prolonged periods.
  • Heavy feeling in limbs: People with atypical depression may experience a sensation of heaviness or leaden paralysis in their arms or legs.
  • Sensitivity to rejection: Rejection sensitivity is heightened in individuals with atypical depression, often leading to social withdrawal or avoidance.

Treatment:

Treatment for atypical depression typically involves a combination of antidepressant medication and psychotherapy.

Commonly prescribed antidepressants include:

  • Selective serotonin reuptake inhibitors (SSRIs): Such as fluoxetine (Prozac) or sertraline (Zoloft)
  • Monoamine oxidase inhibitors (MAOIs): Such as phenelzine (Nardil) or tranylcypromine (Parnate)
  • Other atypical antidepressants: Such as bupropion (Wellbutrin) or mirtazapine (Remeron)

Psychotherapy options for atypical depression may include cognitive-behavioral therapy (CBT), interpersonal therapy (IPT), or psychodynamic therapy.

In some cases, additional adjunctive treatments, such as exercise, light therapy, or electroconvulsive therapy (ECT), may be recommended.